Missing Data in Longitudinal Clinical Trials Part A: Design and Conceptual Issues.
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منابع مشابه
تحلیل به قصد درمان در مطالعات کارآزمایی بالینی: یک مطالعه مروری
Background & Aim: Randomized controlled trials often suffer from two major problems, i.e., noncompliance and missing outcomes. One potential solution to this problem is using the intention-to-treat (ITT) analysis approach. Therefore, the aim of this study was to review the concept of ITT and the most important issues related to it in practice since RCT researchers utilize it as a guide in order...
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Background and Objectives: A major challenge that affects the longitudinal studies is the problem of missing data. Missing in the data may result in the loss of part of the information which reduces the accuracy of the estimator and obtain the results will be biased and inaccurate. Therefore, it is necessary to evaluate the missing data mechanism from a longitudinal research and to consider thi...
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Missing values and dropouts are common issues in longitudinal studies in all areas of medicine and public health. Intent-to-treat (ITT) analysis has become a widely accepted method for the analysis of controlled clinical trials. In most controlled clinical trials, some patients do not complete their intended followup according to the protocol for a variety of reasons; this problem generates mis...
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PSYCHIATRIC ANNALS 38:12 | DECEMBER 2008 In 1993, several of the authors of this issue of Psychiatric Annals wrote an article titled “Some Conceptual and Statistical Issues in the Analysis of Longitudinal Psychiatric Data.” The article provided a timely discussion and illustration of newly developed mixed-effects regression models for the analysis of longitudinal psychiatric data. The article h...
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Missing values occur in studies of various disciplines such as social sciences, medicine, and economics. The missing mechanism in these studies should be investigated more carefully. In this article, some models, proposed in the literature on longitudinal data with dropout are reviewed and compared. In an applied example it is shown that the selection model of Hausman and Wise (1979, Econometri...
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ورودعنوان ژورنال:
- Psychiatric annals
دوره 38 12 شماره
صفحات -
تاریخ انتشار 2008